EC Number   |
General Information |
Reference |
|---|
   1.13.11.12 | evolution |
DNA and amino acid sequence determination and analysis of LOX1 and LOX2 isozymes, phylogenetic analysis, only LOX1:Md:1a exhibits a glycine residue (Gly567) responsible for dual positional specificity and (R)-LOX activity |
742627 |
| 1.13.11.12 | evolution |
genes CmLOX10 and CmLOX13 include all of the typical LOX domains and share 58.11% identity at the amino acid level with each other. The phylogenetic analysis reveals that CmLOX10 and CmLOX13 are members of the type 2 13-LOX subgroup which are known to be involved in biotic and abiotic stress. The two lipoxygenases may play different functions in oriental melon during plant growth and development, CmLOX10 and CmLOX13 enzyme reaction shows that both enzymes produce 13S-hydroperoxides when linoleic acid is used as substrate |
743601 |
| 1.13.11.12 | malfunction |
deletion of lox greatly diminishes density-dependent development of both sclerotia and conidia, resulting in an overall increase in the number of sclerotia and a decrease in the number of conidia at high cell densities. Lox mutants show decreased linoleic acid LOX activity |
701781 |
| 1.13.11.12 | malfunction |
reduced LOX2 expression decreases the release of green leaf volatiles but does not impair jasmonic acid and jasmonic acid-Ile accumulation |
713248 |
| 1.13.11.12 | metabolism |
13-hydroxy-9,11,5-octadecatrienoic acid (13-HOTrE) is produced by the reduction of a 13-LOX product, 13-hydroperoxy-9,11,15-octadecatrienoic acid (by peroxidases), one of the key substrates of jasmonate biosynthesis |
743426 |
| 1.13.11.12 | metabolism |
depending on the regiospecificity of the enzyme, the incorporation of molecular oxygen leads to formation of 9- or 13-fatty acid hydroperoxides, which are used by LOX itself as well as by members of at least six different enzyme families to form a series of biologically active molecules, collectively called oxylipins |
726126 |
| 1.13.11.12 | metabolism |
profiling of oxylipins from young maize roots reveals complex patterns of products mainly originating from the combined actions of 9- and 13-lipoxygenases and allene oxide synthase. A distinctive feature is the high content of the cyclopentenone 10-oxo-11-phytoenoic acid (10-oxo-PEA) |
741974 |
| 1.13.11.12 | metabolism |
the enzyme is involved in the LOX pathway, overview |
742627 |
| 1.13.11.12 | more |
enzyme homology modeling using the crystal structure of linoleate 13-lipoxygenase from Pseudomonas aeruginosa, PDB entry 4G32, as a template |
-, 741748 |
| 1.13.11.12 | more |
non-heme iron lipoxygenase oxidizes C18-polyunsaturated fatty acids to 13S-hydroperoxy derivatives by an antarafacial reaction mechanism where the bis-allylic hydrogen abstraction is the rate-limiting step |
-, 726338 |
