EC Number   |
General Information |
Reference |
|---|
   1.1.3.37 | evolution |
the enzyme belongs to the family of flavoprotein aldonolactone oxidase/dehydrogenases |
-, 725916 |
| 1.1.3.37 | malfunction |
enzyme deletion in Leishmania donovani results in increased pro-inflammatory responses from host immune cells. Enzyme null mutant parasites show growth defect and loss in virulence |
741019 |
| 1.1.3.37 | metabolism |
the enzyme catalyses the last step in ascorbate biosynthesis pathway |
741019 |
| 1.1.3.37 | metabolism |
the enzyme catalyzes the last step in the biosynthesis of L-ascorbic acid involving the conversion of an aldonolactone substrate to ascorbate (or analogues) |
-, 725916 |
| 1.1.3.37 | more |
cysteine residues are required for enzyme activity |
-, 725916 |
| 1.1.3.37 | physiological function |
D-arabinono-1,4-lactone oxidase is required for synthesizing ascorbate in Leishmania |
-, 725916 |
| 1.1.3.37 | physiological function |
transgenic tobacco plants have increased tolerance to methyl viologen-induced oxidative damage and improved tolerance to aluminium toxicity |
741182 |
