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EC Number General Information Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.404metabolism the enzyme participates in the degradation of pentachlorophenol 744327
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.404physiological function a mutant strain lacking functional PcpD has an impaired ability to remove pentachlorophenol from the medium but removes tetrachlorophenol from the medium at the same rate as does the wild-type strain -, 659022
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.404physiological function TCBQ reductase is the second enzyme in the pentachlorophenol degradation pathway. It rescues the nonproductive diradical complex generated by pentachlorophenol hydroxylase via two fast sequential one-electron transfers 740063
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.404physiological function tetrachlorohydroquinone reductase PcpD catalyzes the reduction of tetrachlorohydroquinone to tetrachlorohydroquinone. In the presence of PcpD, tetrachlorohydroquinone formed by pentachlorophenol hydroxylase PcpB is sequestered until it is reduced to the less toxic tetrachlorohydroquinone, protecting the bacterium from the toxic effects of tetrachlorohydroquinone and maintaining flux through the pathway. Deletion of pcpD results in increased sensitivity to phenols that are degraded via a benzoquinone intermediate 741332
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