EC Number   |
General Information |
Reference |
|---|
    1.1.1.318 | evolution |
EGS is structurally related to the shortchain dehydrogenase/reductases, SDRs, and in particular, enzymes in the isoflavone-reductase-like subfamily |
718254 |
| 1.1.1.318 | evolution |
Ocimum basilicum contains 8 isozymes of eugenol synthase, EGS. The enzymes belong to the PIP family, named after the first three identified members, pinoresinollariciresinol reductase (PLR), isoflavone reductase (IFR), and phenylcoumaran benzylic ether reductase (PCBER) |
763161 |
| 1.1.1.318 | evolution |
the phenylpropene-forming eugenol synthase, EGS, belongs to a structural family of NADPH-dependent reductases that also includes isoeugenol synthase, IGS, pinoresinol-lariciresinol reductase, isoflavone reductase, and phenylcoumaran benzylic ether reductase, evolution and function of EGS1 and IGS1, overview |
718314 |
| 1.1.1.318 | malfunction |
downregulation of RcEGS1 expression in flowers by virus-induced gene silencing leads to a reduction of the relative content of eugenol compared to wild-type flowers |
763589 |
| 1.1.1.318 | metabolism |
PGT-enriched BAHD acyltransferases, encoded by genes ObCAAT1 and ObCAAT2, convert coniferyl alcohol to coniferyl acetate which is the first committed step towards eugenol synthesis, followed by reduction of coniferyl acetate to eugenol and acetate catalyzed by eugenol synthase EGS1. Both ObCAAT1 and ObCAAT2 in combination with ObEGS1 produce eugenol The phenylpropene biosynthesis is not coupled to lignification in sweet basil. Plant phenylpropanoid pathway, overview |
763326 |
| 1.1.1.318 | metabolism |
the enzyme is involved in the biosynthesis of phenylpropenes, overview |
718254 |
| 1.1.1.318 | metabolism |
unlike camphor, eugenol accumulates more in roots. But the absence of the eugenol synthase gene in roots indicates long distance transport from aerial tissues. In silico co-expression analysis indicates the potential involvement of ATP-binding cassette, multidrug and toxic compound extrusion, and sugar transporters in eugenol transport. Ocimum spp. display metabolite partitioning between aerial and root tissues, strict partitioning of metabolites between the aerial shoot system (including young leaves, mature leaves, inflorescence, and flowers) and underground root system. Tissue-specific expression of terpenoid and phenylpropanoid pathway related genes in Ocimum kilimandscharicum. Transcriptomic analysis revealed the highest egs1 expression in young leaves followed by that in flowers, both of which accumulated considerably less amounts of eugenol. The sugar transporter(s) might be involved in partitioning eugenol in roots |
763554 |
| 1.1.1.318 | more |
distribution of aromatic volatiles in different parts of the carrot plants, overview |
763553 |
| 1.1.1.318 | more |
ObCAAT1-RNAi transgenic lines show decreased levels of eugenol and accumulation of coniferyl alcohol and its derivatives |
763326 |
| 1.1.1.318 | more |
structure of a ternary complex of EGS bound to the cofactor NADP(H) and a mixed competitive inhibitor (7S,8S)-ethyl (7,8-methylene)-dihydroferulate, binding interactions within the EGS active site, overview |
718254 |
