EC Number   |
General Information |
Reference |
|---|
   1.1.1.214 | evolution |
the conjugated polyketone reductase C2 (CPR-C1) from Candida parapsilosis IFO 0708 belongs to the aldo-keto reductase, AKR, superfamily |
-, 726465 |
| 1.1.1.214 | evolution |
the conjugated polyketone reductase C2 (CPR-C2) from Candida parapsilosis IFO 0708 belongs to the aldo-keto reductase, AKR, superfamily |
-, 724098 |
| 1.1.1.214 | metabolism |
residue Tyr66 functions as a proton donor following hydrogen transfer from NADPH. Thr30 and His128 are critical residues to bind and orient substrate 2-dehydropantolactone |
-, 761008 |
| 1.1.1.214 | more |
catalytic tetrad in the active site of CPR-C2/NADPH |
-, 724098 |
| 1.1.1.214 | more |
CPR-C1 adopted a triose-phosphate isomerase (TIM) barrel fold at the core of the structure in which Thr25 and Lys26 of the GXGTX motif bind uniquely to the adenosine 2-phosphate group of NADPH. Homology structure modeling, overview |
-, 726465 |
