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physiological function
DANN topoisomerase I is a critical DNA-nicking enzyme involved in the process of cell-specific, ligand-driven enhancer activation. The enzyme occupies androgen receptor-enhancers KLK3 and KLK2 and affects the transcriptional program of the prostate cancer cell line LNCaP
physiological function
DNA topoisomerase I alpha is required for adaptive response to light stimulus and flower development
physiological function
the enzyme is required for the termination of floral stem cell maintenance and is required for the repression of WUS expression in flower development. The enzyme decreases nucleosome density which probably allows the binding of factors that either recruit polycomb group proteins or counteract polycomb group-mediated regulation
Results 1 - 3 of 3