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Results 1 - 8 of 8
EC Number General Information Commentary Reference
Show all pathways known for 4.2.1.79Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.79metabolism 2-methylcitrate dehydratase and 1, 2-methylcitrate synthase are involved in energy metabolism and participate in the methylcitrate cycle, which is an important source of energy in the cell -, 713880
Show all pathways known for 4.2.1.79Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.79more construction of enzyme-deficient DELTA prpD mutant. The two genes acnD and prpF, encoding 2-methylcitrate dehydratase (AcnD, EC 4.2.1.117) and 2-methyl-aconitate isomerase (SoPrpF, EC 5.3.3.-) from Shewanella oneidensis together can replace gene prpD in Salmonella enterica. SoAcnD and SePrpD synthesize different methylaconitate isomers. The SoPrpF protein isomerizes the product of the AcnD reaction into the PrpD product. Mutant SoPrpF variants with substitutions of residues K73 or C107 fail to support growth with propionate as the sole source of carbon and energy -, 749113
Show all pathways known for 4.2.1.79Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.79more ipon silver stess 2-methylcitrate dehydratase and 2-methylcitrate synthase are strongly overexpressed -, 713880
Show all pathways known for 4.2.1.79Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.79metabolism the enzyme is involved in the 2-methylcitric acid cycle, overview -, 749113
Show all pathways known for 4.2.1.79Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.79metabolism the enzyme is involved in the 2-methylcitric acid cycle, overview. The three genes, mmgDE and yqiQ (mmgF), provide three of the five steps of the methylcitric acid cycle, encoded in the mmg operon. The fourth step can be supplied by citB (aconitase), and the fifth probably missing step, the propionyl-CoA synthetase, is probably skipped because the beta-oxidation of methyl-branched fatty acids by the enzymes encoded by mmgABC produce propionyl-CoA. The 2-methylisocitrate produced by CitB is converted to pyruvate and succinate by the enzyme YqiQ(MmgF) -, 749113
Show all pathways known for 4.2.1.79Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.79metabolism the enzyme is involved in the methylcitric acid cycle -, 747131
Show all pathways known for 4.2.1.79Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.79physiological function the MmgE enzyme is not a stereospecific 2-methylcitrate dehydratase because it can dehydrate at least two of the four diastereomers of 2-methylcitrate to yield either (E)-2-methylaconitate or (Z)-2-methylaconitate, but the physiological pathways proceed via (Z)-2-methylaconitate, which serves as the substrate for the citB enzyme in the synthesis of 2-methylisocitrate -, 749113
Show all pathways known for 4.2.1.79Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.79physiological function the PrpD enzyme from Escherichia coli is not a stereospecific 2-methylcitrate dehydratase because it can dehydrate at least two of the four diastereomers of 2-methylcitrate to yield either (E)-2-methylaconitate or (Z)-2-methylaconitate, but the physiological pathways proceed via (Z)-2-methylaconitate, which serves as the substrate for the citB enzyme in the synthesis of 2-methylisocitrate 749113
Results 1 - 8 of 8