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Results 1 - 8 of 8
EC Number
General Information
Commentary
Reference
evolution
identification of Sesquiterpene synthase orthologues of sce1440 in the genomes of myxobacterial strains, overview
metabolism
the enzyme is one of only three type I terpene synthases (TSs, sce1440, sce6369, sce8552) and one type II TS (sce4636), responsible for the production of at least 17 sesquiterpenes in Sorangium cellulosum
more
geosmin synthesis (and geosmin synthase expression) appears to be coordinated with cell growth
more
neither full-length ScGS nor constructs of the C-terminal domain can be crystallized, but homology models of the C-terminal domain are constructed based on about 36% sequence identity with the N-terminal domain, analysis of the crystal structure of the N-terminal domain in unliganded or liganded form, overview. Possible alpha,alpha domain architectures as frameworks for bifunctional catalysis
physiological function
deletion of the doxorubicin gene cluster results in increased cell growth rate along with detectable production of geosmin. Overexpression of the spterp13 gene in the Streptomyecs peucetius doxorubicin mutant leads to 2.4fold enhanced production of geosmin
physiological function
geosmin is a powerful odorant with an extremely low human detection threshold of less than 10 parts-per-trillion, and is mainly responsible for the characteristic odor of freshly turned earth. Although geosmin contributes to the pleasant, earthy flavor of beets, it is also a commonly occurring contaminant of musty-tasting water, wine, and fish. Geosmin is not known to cause human disease, but its detection and elimination from potable water sources is a critical environmental and water quality issue
physiological function
mutants with a deleted geoA are unable to produce either germacradienol or geosmin
physiological function
the enzyme is responsible for geosmin biosynthesis. Geosmin is a secondary metabolite responsible for earthy odors. The occurrence of geosmin has great impact on the quality of water environment. Analysis of the geosmin production under d ifferent environments
Results 1 - 8 of 8