EC Number   |
General Information  |
Reference |
|---|
   3.5.1.13 | evolution |
PamH belongs to the amidase signature, AS, enzyme family. The Ser-Ser-Lys catalytic residues are highly conserved, indicating that there is an evolutionary relationship between the enzymes in the AS family |
718672 |
| 3.5.1.13 | evolution |
the enzyme belongs to the amidase signature enzyme family |
718672 |
| 3.5.1.13 | evolution |
the enzyme belongs to the nitrilase superfamily, subfamily in branch 13. The enzyme contains highly conserved E41-K107-C141 catalytic triad which is typical for nitrilase superfamily amidases |
-, 733190 |
| 3.5.1.13 | more |
the aryl acylamidase activity is associated with cobra venom acetylcholinesterase |
711319 |
| 3.5.1.13 | more |
the enzyme maintains a core alpha/beta/alpha structure and the G-(GAV)-S-(GS)2-GX-(GSAE)-(GSAVYCT)-X-(LIVMT)-(GSA)-X6-(GSAT)-X-(GA)-X-(DE)-X-(GA)-X-S-(LIVM)-R-X-P-(GSACTL) sequence motif |
718672 |
| 3.5.1.13 | physiological function |
aryl acylamidase activity of acetylcholinesterase is actively involved in the process of osteoblast differentiation and mineralization |
754722 |
