EC Number   |
General Information |
Reference |
|---|
   3.4.24.85 | evolution |
RseP is highly conserved in both enterocin K1-sensitive and enterocin K1-insensitive bacteria |
772931 |
| 3.4.24.85 | malfunction |
after heat treatment at 44°C, the enzyme knockout mutant cannot grow at all, whereas the wild type recovers from thermal damage quickly |
754665 |
| 3.4.24.85 | malfunction |
an enzyme knockout mutant is more sensitive to 120 mM ammonium chloride than the wild type |
754667 |
| 3.4.24.85 | malfunction |
defects in MBTPS2 most severely affect the tissues with high rates of protein synthesis, such as skin, cartilage or bone |
769304 |
| 3.4.24.85 | malfunction |
enzyme gene ablation is compatible with parasite replication and stage conversion but results in reduced parasite development in late liver stages and in the asexual intra-erythrocytic cycle |
755137 |
| 3.4.24.85 | malfunction |
knockout of slr1821 resulted in defective photosynthesis, compromised translational and transcriptional machinery and redirection of carbon flux. Knockout of slr1821 results in extensive repression in 35% genes of oxidative phosphorylation upon NH4+ stress, including subunits for NADH dehydrogenase, cytochrome c oxidase and ATP synthase thus rendering the defective electron transfer and oxidative phosphorylation to provide energy for cellular processes |
772353 |
| 3.4.24.85 | malfunction |
lack of S2P2 in Arabidopsis thaliana chloroplasts leads to a significant decrease in the level of photosystem I and photosystem II core proteins: PsaB, PsbA, PsbD, and PsbC, as well as polypeptides building both the main lightharvesting antenna (LHC II), Lhcb1 and Lhcb2, as well as Lhcb4 and Lhcb5 polypeptides, constituting elements of the minor, peripheral antenna system |
771686 |
| 3.4.24.85 | metabolism |
activation of the extracytoplasmic function sigma factor sigmaP by beta-lactams in Bacillus thuringiensis requires the site-2 protease RasP |
-, 754811 |
| 3.4.24.85 | more |
mechanistic insights into intramembrane proteolysis by site-2 protease homolog RseP |
-, 775788 |
| 3.4.24.85 | physiological function |
cells defective in the site-2 protease gene have remarkably higher level of superoxide and elevated rates of cell death than wild-type CHO cells. Lack of the site-2 proease gene leads to cells more vulnerable to oxidative stress. Compared with wild-type CHO cells, mutant cells have higher nicotinamide adenine dinucleotide phosphate oxidase activity and lower paraoxonase-2 expression |
735261 |
