Refine search

Search General Information

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 7 of 7
EC Number
General Information
Commentary
Reference
more
autoprocessing mechanism of the enzyme
more
substrate binding-induced zwitterion formation in the catalytic Cys-His dyad of the enzyme, overview
more
the functional unit of Mpro is a homodimer and each subunit contains a His41-Cys145 catalytic dyad. Presence of a complete substrate-binding pocket and oxyanion hole in both protomers. Reversible substrate-induced dimerization is essential for catalysis, molecular mechanism, overview
physiological function
3CLpro is required for viral replication
physiological function
3CLpro is vital for SARS-coronavirus replication
physiological function
the activity of the enzyme toward specific viral protein substrates is required for efficient viral replication
physiological function
the enzyme is required for viral polyprotein processing
Results 1 - 7 of 7