EC Number   |
General Information  |
Reference |
|---|
    2.8.1.8 | malfunction |
the knockout of isoform LIP1p is fatal for early embryo development |
726128 |
| 2.8.1.8 | metabolism |
the enzyme is involved in lipoic acid synthesis |
718133 |
| 2.8.1.8 | physiological function |
a gene disruption mutant and a genes TK2109/TK2248 disruption mutant are not able to grow in a synthetic medium without Ser and lipoic acid. In the absence of biotin, the TK2109/TK2248 double mutant strain displays growth through six serial cultures as in the case of host strain |
-, 760401 |
| 2.8.1.8 | physiological function |
a gene disruption mutant and a genes TK2109/Tkk248 disruption mutant are not able to grow in a synthetic medium without Ser and lipoic acid. In the absence of biotin, the TK2109/TK2248 double mutant strain displays growth through six serial cultures as in the case of host strain |
-, 760401 |
| 2.8.1.8 | physiological function |
isoform LIP1 is indispensable for embryo development and essential for plastids |
726128 |
| 2.8.1.8 | physiological function |
when heterologously expressed in an Escherichia coli LipA mutant, both isoforms Lip1 and Lip2 (Lip1p) are capable of complementing specific growth phenotypes and increasing lipoylation levels of E2 subunits of pyruvate dehydrogenase in vivo |
762170 |
| 2.8.1.8 | physiological function |
when heterologously expressed in an Escherichia coli lipA mutant, both isoforms Lip1 and Lip2 are capable of complementing specific growth phenotypes and increasing lipoylation levels of E2 subunits of pyruvate dehydrogenase in vivo |
762170 |
