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EC Number
General Information
Commentary
Reference
physiological function
a GlmS deletion mutant is defective in growth unless media are supplemented with D-glucosamine. The mutant is highly sensitive to detergents, hydrophobic antibiotics, and bile salts compared to the wild-type. Mutant secretes higher amounts of beta-lactamase than the wild-type in culture supernatant fractions and is attenuated in cell culture models of Salmonella infection
physiological function
glutamine:fructose-6-phosphate amidotransferase is a rate-limiting enzyme in the hexoamine biosynthetic pathway and plays an important role in type 2 diabetes
physiological function
the recombinant enzyme restores glucosamine prototrophy of the Saccharomyces cerevisiae gfa1 null mutant
Results 1 - 3 of 3