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physiological function
Campylobacter jejuni and Campylobacter coli are the main causes of bacterial diarrhea worldwide. In all of these pathogenic organisms, the flagellin proteins are heavily glycosylated with pseudaminic acid (the product of the PseI catalyzed reaction). The presence of 5,7-bis(acetylamino)-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid is required for the proper development of the flagella and is thereby necessary for motility in, and invasion of, the host
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