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Results 1 - 4 of 4
EC Number
General Information
Commentary
Reference
malfunction
lipopolysaccharide isolated from mutants defective in rfaC lack heptose and all other sugars distal to heptose
physiological function
the enzyme catalyzes the incorporation of the first L-heptose into lipopolysaccharide
physiological function
the enzyme is essential for the transfer of the first heptosyl moiety in the core oligosaccharide of lipopolysaccharide
physiological function
the enzyme is involved in the synthesis of the inner core region of lipopolysaccharide. It catalyzes the addition of the first L-glycero-D-manno-heptose (heptose) molecule to one 3-deoxy-D-manno-oct-2-ulosonic acid residue of the Kdo2-lipid A molecule. Heptose is an essential component of the lipopolysaccharide core domain. Its absence results in a truncated lipopolysaccharide associated with the deeprough phenotype causing a greater susceptibility to antibiotic and an attenuated virulence for pathogenic Gram-negative bacteria
Results 1 - 4 of 4