EC Number |
General Information |
Reference |
---|
2.3.1.286 | evolution |
Phno is a member of the Gcn5-related N-acetyltransferase (GNAT) family. GNATs acetylate a broad range of substrates, including antibiotics, polyamines, amino acids, nucleotides, tRNAs, proteins, and peptides |
757557 |
2.3.1.286 | evolution |
YfiQ is a member of the Gcn5-related N-acetyltransferase (GNAT) family. GNATs acetylate a broad range of substrates, including antibiotics, polyamines, amino acids, nucleotides, tRNAs, proteins, and peptides |
757557 |
2.3.1.286 | evolution |
Yiac is a member of the Gcn5-related N-acetyltransferase (GNAT) family. GNATs acetylate a broad range of substrates, including antibiotics, polyamines, amino acids, nucleotides, tRNAs, proteins, and peptides |
757557 |
2.3.1.286 | evolution |
YjaB is a member of the Gcn5-related N-acetyltransferase (GNAT) family. GNATs acetylate a broad range of substrates, including antibiotics, polyamines, amino acids, nucleotides, tRNAs, proteins, and peptides |
757557 |
2.3.1.286 | malfunction |
NAD+-dependent SIRT1 deactivation has a key role on ischemia-reperfusion-induced apoptosis |
739745 |
2.3.1.286 | malfunction |
SIRT1 depletion by RNA interference attenuates capsaicin-induced apoptosis in A-549 cancer cells and autophagy in MRC-5 cells |
738438 |
2.3.1.286 | metabolism |
acetylation of Lys413 decreases catalysis and SIRT3 reactivates isocitrate dehydrogenase 2 upon deacetylation. SIRT3-dependent deacetylation of isocitrate dehydrogenase 2 suppresses cellular stress by reactive oxygen species (ROS). Acetylation of Lys413 is regulated by SIRT3 in response to calorie and glucose restriction |
729982 |
2.3.1.286 | metabolism |
caloric restriction can extend life-span by inducing SIRT1 expression and promoting the long-term survival of irreplaceable cells |
730962 |
2.3.1.286 | metabolism |
isoform SIRT3 levels modulate mitochondrial protein folding |
738661 |
2.3.1.286 | metabolism |
Sir2 is involved in the regulation of p53 function via deacetylation |
729560 |