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EC Number General Information Commentary Reference
Display the reaction diagram Show all sequences 2.1.1.198malfunction strain DELTAyraL produces monomethylated cytosine1402 instead of dimethylated C1402 produced by the wild-type enzyme 705980
Display the reaction diagram Show all sequences 2.1.1.198physiological function both the 2'-O-methylation (catalyzed by RsmI) and N4-methylation of C1402 (catalyzed by RsmH) are needed for efficient initiation at the UUG and GUG codon. m4Cm1402 in the 16S rRNA modulates the accuracy of P-site function. The modification is needed for efficient translation initiation at the UUG and GUG codons 705980
Display the reaction diagram Show all sequences 2.1.1.198malfunction enzyme deletion affects efficiency of non-AUG initiation and the fidelity of translation -, 735241
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