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EC Number
General Information
enzyme is part of the degradation pathway of 4-nitrophenol which is a priority environmental pollutant
HqdC gene is part of a gene cluster associated with hydroquinone degradation into 3-oxoadipate
highly conserved residues C281 and E247 are identified to be critical for its catalytic activity, and flexible docking studies of the enzyme-substrate system predict the interactions between PnpE and its substrate 4-hydroxymuconic semialdehyde, flexible docking of substrate to PnpE, molecular docking analysis, overview
physiological function
the pnpE-encoded enzyme gamma-hydroxymuconic semialdehyde dehydrogenase catalyzes the reduction of 4-hydroxymuconic semialdehyde to maleylacetate in Pseudomonas sp. strain WBC-3, playing a key role in the catabolism of toxic para-nitrophenol to Krebs cycle intermediates
Results 1 - 4 of 4