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EC Number Expression Commentary Reference
Show all pathways known for 3.5.4.10Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.10up high glucose up-regulates the expression and activity of the enzyme and increases the levels of reactive oxygen species and methylglyoxal-derived advanced glycation end products. Overexpression of the enzyme (atic-1) decreases the lifespan and head motility and increases neuronal damage under both standard and high glucose conditions 757213
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