EC Number |
Expression |
Reference |
---|
3.4.24.B10 | down |
a significant decrease in ADAMTS-12 mRNA levels is detected in extravillous cytotrophoblasts cultured in the presence of transforming growth factor-beta1 (1 ng/ml) for 24 - 48 h |
720822 |
3.4.24.B10 | more |
ADAM12-L mRNA expression is an independent prognostic factor in resected p-stage I lung adenocarcinoma, and is significantly correlated with tumor differentiation stage and postoperative cancer recurrence |
712898 |
3.4.24.B10 | up |
5-fluorouracil induces expression of the enzyme isoform ADAM12-L but not ADAM12-S in breast cancer cells and in recurrent breast cancer tissues |
755485 |
3.4.24.B10 | up |
ADAM12 is dynamically upregulated and under the transcriptional control of protein kinase A |
733623 |
3.4.24.B10 | up |
ADAM12 mRNA expression is elevated 10-30fold in malignant breast tissue and metastatic lymph nodes |
719935 |
3.4.24.B10 | up |
ADAMTS-12 mRNA levels in extravillous cytotrophoblasts are significantly higher than those detected in JEG-3 cell. Interleukin-1beta causes a continuous and significant increase in ADAMTS-12 mRNA levels in extravillous cytotrophoblasts over time in culture |
720822 |
3.4.24.B10 | up |
expression by astrocytes is increased in brain regions affected by cuprizone-induced demyelination |
711642 |
3.4.24.B10 | up |
expression of ADAM12 is enriched in interleukin-17 secreting T cells |
735109 |
3.4.24.B10 | up |
inhibition of canonical Notch signaling increases ADAM12 long isoform expression and trophoblast invasion |
734873 |
3.4.24.B10 | up |
spatiotemporally expressed in decidualizing stromal cells in intact pregnant females and in pseudopregnant mice undergoing artificially induced decidualization |
711706 |