EC Number   |
Expression |
Reference |
|---|
   3.4.24.81 | down |
ADAM10 mRNA is lowered in moderate to severe Alzheimers disease |
719416 |
| 3.4.24.81 | up |
ADAM10 levels are significantly enhanced on germinal center B cells |
720159 |
| 3.4.24.81 | up |
amount and activity of ADAM10 is increased by application of low doses of statins |
719416 |
| 3.4.24.81 | up |
cultured HL-60 neutrophils exposed to tobacco smoke extract show increased enzyme content, cleavage of the molecule into its active form, and release of microvesicles carrying mature enzyme |
755575 |
| 3.4.24.81 | up |
enzyme expression is significantly elevated in nasopharyngeal carcinoma |
753146 |
| 3.4.24.81 | up |
enzyme levels are higher in sections from patients with anterior disk displacement with and without reduction compared to normal temporomandibular joint disks |
752407 |
| 3.4.24.81 | up |
retinoids induce gene expression of ADAM10. The vitamin A analog acitretin stimulates ADAM10 promoter activity with an EC50 of 0.0015 mM |
708458 |
| 3.4.24.81 | up |
the enzyme is upregulated at injury sites and in denervated areas of the brain following brain injury |
753694 |
