EC Number   |
Expression |
Reference |
|---|
   3.4.22.64 | more |
induction of procaspase-11 expression is delayed in Myd88-/- macrophages infected with DELTAFlag Salmonella typhimurium, although procaspase-11 processing itself remains intact |
731744 |
| 3.4.22.64 | more |
Lipopolysaccharide treatment or type I IFN treatment alone does not cause caspase-11-dependent cell death |
731611 |
| 3.4.22.64 | more |
poly(ADP-ribose) polymerase-1, PARP-1, regulates the expression of caspase-11 following lipopolysaccharide stimulation. PARP-1 is recruited to the caspase-11 promoter region containing predicted nuclear factor (NF)-kappaB-binding sites, but PARP-1 enzymatic activity is not required for the caspase-11 upregulation. PARP-1 can regulate the induction of caspase-11 at a transcriptional level. PARP-1 participates in the activation of caspase-11 promoter as a coactivator of NF-kappaB |
717195 |
| 3.4.22.64 | up |
bacterial lipopolysaccharide stimulation of caspase-11 expression in several mouse tissues, particularly in the spleen |
731613 |
| 3.4.22.64 | up |
cytosolic infection of cells with Burkholderia species and cytyosolic mutants of Salmonella typhimurium and Legionella pneumophila trigger the enzyme |
-, 732915 |
| 3.4.22.64 | up |
induction of caspase-11 is dependent on NF-kappaB. PARP-1 participates in the activation of caspase-11 promoter as a coactivator of NF-kappaB. Lipopolysaccharide induce the enzyme expression |
717195 |
| 3.4.22.64 | up |
ischemia induces expression in astrocytes |
709623 |
| 3.4.22.64 | up |
type I IFN signaling is sufficient to induce caspase-11 upregulation and processing. The adaptor protein TRIF upregulates procaspase-11 expression, and this upregulation is required for caspase-11 processing and activation |
731611 |
