EC Number   |
Expression |
Reference |
|---|
   3.4.22.57 | down |
c-Rel is a negative regulator of caspase-4, e.g. in EBV lymphoblastoid cells |
718292 |
| 3.4.22.57 | down |
the dominant negative form of IkappaBalpha suppresses the expression of caspase-4 |
732677 |
| 3.4.22.57 | more |
c-Rel as well as other endoplasmic reticulum stress genes directly modulate expression of caspase-4 |
718292 |
| 3.4.22.57 | up |
apoptosis-independent cell death is accompanied by increased expression of the inflammatory marker, caspase-4. Caspase-4 is upregulated in Pt1 cells and induced by interferons |
718292 |
| 3.4.22.57 | up |
caspase-4 protein expression is strongly induced in the lesional stratum corneum of patients suffering from psoriasis, a common chronic inflammatory disease |
717945 |
| 3.4.22.57 | up |
enhancement of nuclear factor-kappaB activity by p65 (RelA) overexpression increases the expression of caspase-4 at both mRNA and protein levels |
732677 |
| 3.4.22.57 | up |
mRNA expression of the pro-form of caspase-4 is up-regulated 2fold after poly-I:C stimulation |
732238 |
| 3.4.22.57 | up |
tunicamycin and thapsigargin induce caspase-4 mRNA expression and protein activation |
718027 |
