EC Number   |
Expression |
Reference |
|---|
   3.4.21.B10 | more |
no change in KLK6 expression is observed upon treatment of T47D cells with trichostatin A |
707981 |
| 3.4.21.B10 | up |
highly up-regulated in several types of cancer, where its increased activity promotes cancer invasion and metastasis |
754166 |
| 3.4.21.B10 | up |
injury-induced elevations in enzyme level |
731396 |
| 3.4.21.B10 | up |
Klk6 RNA is up-regulated in splenocytes in a viral capsid protein dependent fashion, using recombinnatly expressed encoding Theiler's murine encephalomyelitis virus TMEV VP1 and VP2 capsid proteins, and in THP-1 monocytes activated by phorbol 12-myristate-13-acetate and lipopolysaccharide |
731563 |
| 3.4.21.B10 | up |
SJL mice infecteion with Theiler's murine encephalomyelitis virus causes an increase in enzyme expression in the spinal cord and in splenocytes. Klk6 RNA is up-regulated in splenocytes in a viral capsid protein dependent fashion, using recombinnatly expressed encodingTMEVVP1 andVP2 capsid proteins, and in THP-1 monocytes activated by phorbol 12-myristate-13-acetate and lipopolysaccharide |
-, 731563 |
| 3.4.21.B10 | up |
stepwise expression increase from metaplasia to dysplasia and invasive tumors, significantly increased enzyme expression in early invasive cancer, overview |
731898 |
| 3.4.21.B10 | up |
the enzyme is up-regulated in ovarian cancer |
731397 |
| 3.4.21.B10 | up |
treatment of MDA-MB-231 and T47D breast tumor cell lines with 5-aza-2'-deoxycytidine results in significant induction of KLK6 expression |
707981 |
