EC Number   |
Expression |
Reference |
|---|
   3.4.21.108 | down |
124 endometrial tissue specimens including 88 cancers and 36 normal endometria are analyzed. HtrA2 protein levels are significantly lower in endometrial cancer cells compared to normal cells |
710167 |
| 3.4.21.108 | down |
ablation of HtrA2 activity using RNAi in the human osteosarcoma U2OS cells prevents the cleavage of Wilms'tumor suppressor protein WT1 under apoptotic conditions |
709955 |
| 3.4.21.108 | down |
after specific HtrA2 downregulation using RNAi, increased cell viability is measured in H2O2-treated ARPE-19 cells |
708821 |
| 3.4.21.108 | down |
Omi/HtrA2 siRNA decreases the cleavage of annexin A2 lung epithelial adenocarcinoma cell A549 under both serum withdrawal and cisplatin treatment |
709872 |
| 3.4.21.108 | down |
S-nitrosoglutathione treatment significantly decreases mitochondrial Omi/HtrA2 content after 8 h of exposure in endothelial cells |
713539 |
| 3.4.21.108 | down |
the expression level of HtrA2/Omi decreases with endoplasmic reticulum stress induction in 6-hydroxydopamine-treated SH-SY5Y cells |
732357 |
| 3.4.21.108 | up |
S-nitrosoglutathione treatment significantly increases cytosolic Omi/HtrA2 content after 8 h of exposure in endothelial cells |
713539 |
