EC Number   |
Expression |
Reference |
|---|
   3.4.17.23 | down |
angiotensin II downregulates ACE2, but increases the expression of vascular endothelial growth factor and type receptor AT1-R, overview |
710171 |
| 3.4.17.23 | down |
central angiotensin II type 1 receptors reduce ACE2 expression/activity in hypertensive mice |
708683 |
| 3.4.17.23 | down |
infection with highly pathogenic avian influenza A H5N1 virus results in downregulation of angiotensin-converting enzyme 2 (ACE2) expression in the lung |
732569 |
| 3.4.17.23 | down |
mechanisms exist by which SARS-CoV-2 induces shedding of ACE2, together with downregulation of ACE2 gene expression |
763771 |
| 3.4.17.23 | down |
mice infected with influenza H7N9 virus downregulate ACE2 protein markedly on day 3 after infection |
732911 |
| 3.4.17.23 | down |
miR-421 (miRNA) downregulates the expression of ACE2 in human cells by interacting with a specific sequence in its 3'-UTR and thereby repressing translation |
731675 |
| 3.4.17.23 | down |
SARS-CoV downregulates ACE2 protein by binding its spike protein, contributing to severe lung injury |
753431 |
| 3.4.17.23 | down |
treatment of A-549 lung epithelial cells with 17-beta-estradiol reduces the cellular mRNA levels of ACE2 and TMPRSS2 mRNA, while not affecting FURIN expression |
764554 |
| 3.4.17.23 | more |
ACE2 mRNA and protein expression in murine lung, heart and aorta is not influenced by ibuprofen |
764930 |
| 3.4.17.23 | more |
presence of ibuprofen, flurbiprofen, etoricoxib or paracetamol have no effect on ACE2 mRNA/protein expression and activity in the Caco-2 cell model |
764930 |
