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EC Number Expression Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.116down DAGLalpha expression is dramatically downregulated when neural stem (NS) cells are differentiated toward a gamma-aminobutyric acidergic neuronal phenotype. Like DAGLalpha, Sp1 is downregulated during neuronal differentiation. The dnSp1 significantly decreases the luciferase activity of P6 relative to GC-box-deleted P6. DAGLalpha expression is dynamically regulated in Cor-1 cells, being dramatically downregulated when the cells are differentiated toward a GABAergic neuronal phenotype. DAGLalpha protein is downregulated in Cor-1 cells during neuronal differentiation 761722
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.116more the core DAGLa promoter is under a different regulatory control in the different cell types and identify two independent elements that can specifically regulate expression in Cor-1 cells. The GC-box is required for DAGLa core promoter activity in Cor-1 cells but not in 3T3 cells 761722
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