EC Number |
Expression |
Reference |
---|
2.8.2.4 | down |
a confirmed repressor of EST gene in human primary hepatocytes and hepatocellular carcinoma Huh7 cells is pregnane X receptor (PXR), when the PXR is activated by rifampicin. Aryl hydrocarbon receptor (AhR) activation has also been shown to suppress EST expression |
760317 |
2.8.2.4 | down |
enzyme expression is dramatically reduced in differentiated 3T3-L1 cells and mature primary adipocytes |
725979 |
2.8.2.4 | down |
in liver SULT1E1 is repressed by xenobiotic activators of the pregnane X receptor and aryl hydrocarbon receptor peroxisome proliferator |
761169 |
2.8.2.4 | down |
reduced SULT1E1 expression is observed in the eutopic endometrium relative to the superficial lesions as well as during the follicular phase of the menstrual cycle |
738929 |
2.8.2.4 | down |
rSULT1E1 expression is reduced in the liver tissues of the N-ethyl-N-nitrosourea-administered group and in the estradiol-treated group compared to the control group |
-, 761874 |
2.8.2.4 | down |
WY14643 decreases SULT1E1 mRNA and SULT1E1 protein levels |
739089 |
2.8.2.4 | more |
dopamine has no significant effect on enzyme expression in both sexes |
738751 |
2.8.2.4 | up |
enzyme activity is significantly higher in the endometrial carcinoma than in normal endometrial tissues |
716213 |
2.8.2.4 | up |
enzyme expression is induced by testosterone in female mice |
723909 |
2.8.2.4 | up |
factors HNF4alpha and Nrf2 induce the expression of enzyme SULT1E1. Factor HNF4alpha is induced by oxidative stress, and factor Nrf2 is induced by estradiol via the P13K/GSK3B pathway |
761875 |