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EC Number	Expression	Commentary	Reference
2.7.1.153	more	gain of copy number of PIK3CA gene by gene amplification in mantle cell lymphoma is one mechanism of oncogenic activation of PI3K. Expression of PIK3CA in mantle cell lymphoma correlates with gene copy numbers determined by real-time PCR, overview	708158
2.7.1.153	up	upregulation of class I PI3K isozymes in cancer cells	710598
2.7.1.153	up	virulent Legionella pneumophila infection induces PI3K in human macrophages, while PI3K and protein kinase B, PKB/Akt, activities are lower in macrophages infected with an avirulent bacterial strain	710351

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Release 2023.1 (January 2023)