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EC Number	Expression	Commentary	Reference
2.7.1.113	down	enzyme expression is downregulated by didanosine (2',3'-dideoxyinosine) to about 40%	737599
2.7.1.113	down	treatment with 3'-azido-2',3'-dideoxythymidine (zidovudine) treatment leads to downregulation of the mitochondrial enzyme in U2OS cells. Incubation with 1 mM tert-butylhydroperoxide results in 80% and 65% reductions in mitochondrial protein levels. Similarly, incubation with 2 mM diamide leads to about 50% decreases in enzyme expression	737461

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Release 2023.1 (January 2023)