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Results 1 - 3 of 3
EC Number Expression Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.224down EXT1 is significantly decreased in MCF7 cells compared with the non-tumorigenic MCF10A cells, while no significant difference is observed between the two triple-negative cell lines, MDA-MB-231 and HCC38, and the ER- and PR-positive MCF10A cells 758941
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.224down the expression of EXT2 is reduced in all cancer cell lines 758941
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.224down the overall transcriptional activity of the main heparan sulfate biosynthesis-involved genes (EXT1, EXT2, NDST1,NDST2, GLCE, HS2ST1, HS3ST1, HS3ST2, HS6ST1, HS6ST2, SULF1, SULF2, HPSE) is decreased by 1.5-2fold in Grade II-III glioma (p < 0.01) and by 3-fold in Grade IV glioma (glioblastoma multiforme, GBM) (p < 0.05), as compared with the para-tumourous tissue 759360
Results 1 - 3 of 3