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1.3.1.85
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TetR-type activator CcrR regulates the expression of crotonyl-CoA reductase/carboxylase. A ccrR null mutant strain ismpaired in its ability to grow on C1 and C2 compounds, correlating with the reduced activity of crotonyl-CoA reductase/carboxylase. The activity of the promoter required for ccr expression decreases as much as 50% in the absence of ccrR compared to wild-type. CcrR directly binds to the region upstream of the katA-ccr promoter
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725271
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although the reaction is reversible, the activity of crotonyl-CoA carboxylase/reductase is up-regulated at least 60fold for Rhodobacter sphaeroides during growth with acetate versus succinate
710982
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