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EC Number Expression Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.14.18.B1up upregulation of histone H3K27 demethylase JMJD3 by long noncoding RNA HOTAIR, i.e. homeobox transcript antisense intergenic RNA, a kind of non-protein coding transcripts longer than 200 nucleotides. HOTAIR is an important promoter in metastasis of renal cell carcinoma and also plays a dual regulatory role in chromatin state by effecting both histone metylation and demethylation at different gene loci. HOTAIR can affect histone H3K27 methylation and its target genes' expression 745947
Display the word mapDisplay the reaction diagram Show all sequences 1.14.18.B1up upregulation of JMJD3 expression in scratch-wounded keratinocytes 745509
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