EC Number   |
Expression |
Reference |
|---|
   1.14.11.69 | down |
checkpoint kinase Rad53 negatively modulates Rph1 protein level |
-, 726071 |
| 1.14.11.69 | down |
the crucial checkpoint protein Rad53 acts as an upstream regulator of Rph1 and dominates the phosphorylation of Rph1 that is required for efficient PHR1 expression and the dissociation of Rph1 |
-, 726071 |
| 1.14.11.69 | down |
upon 4-hydroxytamoxifen treatment, Jmjd2a and Jmjd2b become undetectable by Western blot, while expression levels for other Jmjd2 family members are unaltered |
-, 744785 |
| 1.14.11.69 | more |
Jmjd2c expression is unaffected by 4-hydroxytamoxifen treatment, while Jmjd2a and Jmjd2b are downregulated |
-, 744785 |
| 1.14.11.69 | up |
KDM4A expression is upregulated in phosphatase and tensin homolog knockout mouse prostate tissue |
764401 |
| 1.14.11.69 | up |
mRNA and protein levels of Jmjd2a are significantly increased in the neurons of mouse undergoing neuropathic pain |
764639 |
| 1.14.11.69 | up |
Rph1 is phosphorylated under oxidative stress, which leads to Rph1 dissociation and transcriptional activation. Rad53 may be the key kinase essential for Rph1 phosphorylation on oxidative stress with H2O2 treatment |
-, 726071 |
