Refine search

Search Expression

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 10 of 13 > >>
EC Number
Expression
Commentary
Reference
down
porcine reproductive and respiratory syndrome virus infection significantly downregulates the expression of the enzyme in cells
down
the enzyme mRNA expression level is originally low in myelodysplasia/leukemia cell lines. Enzyme knockdown partially protects the cells from decitabine-induced cell death
more
enzyme expression is not induced by interferons in human cells and knockdown of STAT-1 has no effect on the induction of the enzyme
up
activation of the innate immune system by TLR ligands induces 25-hydroxycholesterol production which results in suppression of IgA class switching in B cells
up
both IFN-alpha- and IFN-gamma induce the enzyme in bone marrow-derived macrophages
up
exposure to DNA methyltransferase inhibitors and decitabine enhances enzyme mRNA expression in myelodysplasia/leukemia cell lines
up
induction of Ch25h is JAK- and STAT1-dependent, overview
up
induction of CYP3A by pregnenolone-16 alpha-carbonitrile causes accumulation of 25-hydroxycholesterol in cell line AML12 derived from mouse liver, the induction is not suppressed by the addition of desmosterol. Although the transcription of Ch25h is also upregulated by addition of pregnenolone-16 alpha-carbonitrile, the protein level of CH25H is not elevated. Desmosterol does not affect the expression of cellular CYP3A protein, but CH25H protein level is obviously decreased by desmosterol treatment
up
pseudorabies virus infection of porcine alveolar macrophages is attenuated by enzyme overexpression (24 h post infection)
up
the enzyme expression in primary human hepatocytes is primarily and transiently induced by type I interferon. Infection with hepatitis C virus causes up-regulation of the enzyme in vivo
Results 1 - 10 of 13 > >>