EC Number   |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism |
PubMed ID |
|---|
    5.3.3.5 | 714753 |
1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed sigma and human DELTA8-DELTA7 sterol isomerase ligands with antiproliferative and P-glycoprotein inhibitory activity |
ChemMedChem |
6 |
73-80 |
2011 |
Homo sapiens |
21069657 |
| 5.3.3.5 | 653232 |
Cholesterol biosynthesis from lanosterol: differential inhibition of sterol DELTA8-isomerase and other lanosterol-converting enzymes by tamoxifen |
Mol. Cells |
8 |
233-239 |
1998 |
Rattus norvegicus |
9638657 |
| 5.3.3.5 | 649702 |
Cholesterol biosynthesis from lanosterol: molecular cloning, chromosomal localization, functional expression and liver-specific gene regulation of rat sterol DELTA8-isomerase, a cholesterogenic enzyme with multiple functions |
Biochem. J. |
353 |
689-699 |
2001 |
Rattus norvegicus |
11171067 |
| 5.3.3.5 | 649855 |
Histidine77, glutamic acid81, glutamic acid123, threonine126, asparagine194, and tryptophan197 of the human emopamil binding protein are required for in vivo sterol DELTA8-DELTA7 isomerization |
Biochemistry |
38 |
1119-1127 |
1999 |
Homo sapiens |
9894009 |
| 5.3.3.5 | 690830 |
Identification of essential amino acid residues in a sterol 8,7-isomerase from Zea mays reveals functional homology and diversity with the isomerases of animal and fungal origin |
Biochem. J. |
414 |
247-259 |
2008 |
Saccharomyces cerevisiae |
18459942 |
| 5.3.3.5 | 690830 |
Identification of essential amino acid residues in a sterol 8,7-isomerase from Zea mays reveals functional homology and diversity with the isomerases of animal and fungal origin |
Biochem. J. |
414 |
247-259 |
2008 |
Zea mays |
18459942 |
| 5.3.3.5 | 653487 |
Isolation and characterization of an Arabidopsis thaliana C-8,7 sterol isomerase: functional and structural similarities to mammalian C-8,7 sterol isomerase/emopamil-binding protein |
Plant Mol. Biol. |
38 |
807-815 |
1998 |
Arabidopsis thaliana |
9862498 |
| 5.3.3.5 | 662248 |
Molecular characterization of the microsomal tamoxifen binding site |
J. Biol. Chem. |
279 |
34048-34061 |
2004 |
Homo sapiens |
15175332 |
| 5.3.3.5 | 693574 |
Novel 4-(4-aryl)cyclohexyl-1-(2-pyridyl)piperazines as DELTA8-DELTA7 sterol isomerase (emopamil binding protein) selective ligands with antiproliferative activity |
J. Med. Chem. |
51 |
7523-7531 |
2008 |
Homo sapiens |
19053780 |
| 5.3.3.5 | 653279 |
Pharmacological analysis of sterol DELTA8-DELTA7-isomerase proteins with [3H]ifenprodil |
Mol. Pharmacol. |
54 |
591-598 |
1998 |
Saccharomyces cerevisiae |
9730919 |
