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Results 1 - 10 of 33 > >>
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EC Number BRENDA No. Title Journal Volume Pages Year Organism PubMed ID
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.86761268 Cyclic GMP-AMP synthase is essential for cytosolic double-stranded DNA and fowl adenovirus serotype 4 triggered innate immune responses in chickens Int. J. Biol. Macromol. 146 497-507 2020 Gallus gallus 31923489
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.86761638 Cyclic GMP-AMP synthase is the cytosolic sensor of Plasmodium falciparum genomic DNA and activates type I IFN in malaria J. Immunol. 200 768-774 2018 Homo sapiens 29212905
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.86762288 Cyclic GMP-AMP synthase promotes the inflammatory and autophagy responses in Huntington disease Proc. Natl. Acad. Sci. USA 117 15989-15999 2020 Mus musculus 32581130
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.86762288 Cyclic GMP-AMP synthase promotes the inflammatory and autophagy responses in Huntington disease Proc. Natl. Acad. Sci. USA 117 15989-15999 2020 Homo sapiens 32581130
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.86762288 Cyclic GMP-AMP synthase promotes the inflammatory and autophagy responses in Huntington disease Proc. Natl. Acad. Sci. USA 117 15989-15999 2020 Mus musculus C57BL/6J 32581130
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.86761723 Discovery of small-molecule cyclic GMP-AMP synthase inhibitors J. Org. Chem. 85 1579-1600 2020 Homo sapiens 31829590
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.86761514 Dysfunctional telomeres trigger cellular senescence mediated by cyclic GMP-AMP synthase J. Biol. Chem. 295 11144-11160 2020 Homo sapiens 32540968
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.86761597 In silico screening-based discovery of novel inhibitors of human cyclic GMP-AMP synthase a cross-validation study of molecular docking and experimental testing J. Chem. Inf. Model. 60 3265-3276 2020 Homo sapiens 32459092
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.86761781 Small molecule inhibition of cyclic GMP-AMP synthase ameliorates sepsis-induced cardiac dysfunction in mice Life Sci. 260 118315 2020 Mus musculus 32835697
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.86762338 The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition Protein Sci. 26 2367-2380 2017 Homo sapiens 28940468
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