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Results 1 - 10 of 83 > >>
EC Number BRENDA No. Title Journal Volume Pages Year Organism PubMed ID
Show all pathways known for 2.1.2.3Display the word mapDisplay the reaction diagram Show all sequences 2.1.2.3756109 Analysis of substrate binding in individual active sites of bifunctional human ATIC Biochim. Biophys. Acta 1866 254-263 2018 Homo sapiens 29042184
Show all pathways known for 2.1.2.3Display the word mapDisplay the reaction diagram Show all sequences 2.1.2.3756701 Characterization of AICAR transformylase/IMP cyclohydrolase (ATIC) from Staphylococcus lugdunensis FEBS J. 284 4233-4261 2017 Staphylococcus lugdunensis 29063699
Show all pathways known for 2.1.2.3Display the word mapDisplay the reaction diagram Show all sequences 2.1.2.3756196 Colocalization and sequential enzyme activity in aqueous biphasic systems experiments and modeling Biophys. J. 109 2182-2194 2015 Homo sapiens 26588576
Show all pathways known for 2.1.2.3Display the word mapDisplay the reaction diagram Show all sequences 2.1.2.3756643 Design, synthesis and biological evaluation of 6-substituted pyrrolo[2,3-d]pyrimidines as dual inhibitors of TS and AICARFTase and as potential antitumor agents Eur. J. Med. Chem. 115 245-256 2016 Homo sapiens 27017552
Show all pathways known for 2.1.2.3Display the word mapDisplay the reaction diagram Show all sequences 2.1.2.3757394 Discovery of N-(6-fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a potent and selective nonclassical antifolate aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT) inhibitor J. Med. Chem. 60 9599-9616 2017 Homo sapiens 29072452
Show all pathways known for 2.1.2.3Display the word mapDisplay the reaction diagram Show all sequences 2.1.2.3757213 High-glucose toxicity is mediated by AICAR-transformylase/IMP cyclohydrolase and mitigated by AMP-activated protein kinase in Caenorhabditis elegans J. Biol. Chem. 293 4845-4859 2018 Caenorhabditis elegans 29414769
Show all pathways known for 2.1.2.3Display the word mapDisplay the reaction diagram Show all sequences 2.1.2.3756648 Novel 6-substituted benzoyl and non-benzoyl straight chain pyrrolo[2,3-d]pyrimidines as potential antitumor agents with multitargeted inhibition of TS, GARFTase and AICARFTase Eur. J. Med. Chem. 139 531-541 2017 Homo sapiens 28830032
Show all pathways known for 2.1.2.3Display the word mapDisplay the reaction diagram Show all sequences 2.1.2.3757662 The last enzyme of the de novo purine synthesis pathway 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC) plays a central role in insulin signaling and the Golgi/endosomes protein network Mol. Cell. Proteomics 14 1079-1092 2015 Rattus norvegicus 25687571
Show all pathways known for 2.1.2.3Display the word mapDisplay the reaction diagram Show all sequences 2.1.2.3757625 Utilisation of 10-formyldihydrofolate as substrate by dihydrofolate reductase (DHFR) and 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) tranformylase/IMP cyclohydrolase (PurH) in Escherichia coli Microbiology 164 982-991 2018 Escherichia coli 29799386
Show all pathways known for 2.1.2.3Display the word mapDisplay the reaction diagram Show all sequences 2.1.2.3757625 Utilisation of 10-formyldihydrofolate as substrate by dihydrofolate reductase (DHFR) and 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) tranformylase/IMP cyclohydrolase (PurH) in Escherichia coli Microbiology 164 982-991 2018 Escherichia coli K12 29799386
Results 1 - 10 of 83 > >>