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Results 1 - 10 of 12 > >>
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EC Number BRENDA No. Title Journal Volume Pages Year Organism PubMed ID
Display the reaction diagram Show all sequences 2.1.1.314756875 Diphthamide modification of eEF2 is required for gut tumor-like hyperplasia induced by oncogenic Ras Genes Cells 25 76-85 2020 Drosophila sp. (in: flies) 31828897
Display the reaction diagram Show all sequences 2.1.1.314758174 Importance of diphthamide modified EF2 for translational accuracy and competitive cell growth in yeast PLoS ONE 13 e0205870 2018 Saccharomyces cerevisiae 30335802
Display the reaction diagram Show all sequences 2.1.1.314758510 Influence of DPH1 and DPH5 protein variants on the synthesis of diphthamide, the target of ADPRibosylating toxins Toxins 9 E78 2017 Homo sapiens 28245596
Display the reaction diagram Show all sequences 2.1.1.314758218 Loss of diphthamide pre-activates NF-kappaB and death receptor pathways and renders MCF7 cells hypersensitive to tumor necrosis factor Proc. Natl. Acad. Sci. USA 112 10732-10737 2015 Homo sapiens 26261303
Display the reaction diagram Show all sequences 2.1.1.314757303 QM/MM studies of Dph5 - a promiscuous methyltransferase in the eukaryotic biosynthetic pathway of diphthamide J. Chem. Inf. Model. 58 1406-1414 2018 Saccharomyces cerevisiae 29927239
Display the reaction diagram Show all sequences 2.1.1.314757695 The diphthamide modification pathway from Saccharomyces cerevisiae - revisited Mol. Microbiol. 94 1213-1226 2016 Saccharomyces cerevisiae 25352115
Display the reaction diagram Show all sequences 2.1.1.314485689 Biosynthesis of diphthamide in Saccharomyces cerevisiae. Partial purification and characterization of a specific S-adenosylmethionine:elongation factor 2 methyltransferase J. Biol. Chem. 263 11692-11696 1988 Saccharomyces cerevisiae 3042777
Display the reaction diagram Show all sequences 2.1.1.314485689 Biosynthesis of diphthamide in Saccharomyces cerevisiae. Partial purification and characterization of a specific S-adenosylmethionine:elongation factor 2 methyltransferase J. Biol. Chem. 263 11692-11696 1988 Saccharomyces cerevisiae ATCC 204508 3042777
Display the reaction diagram Show all sequences 2.1.1.314729901 Dph7 catalyzes a previously unknown demethylation step in diphthamide biosynthesis J. Am. Chem. Soc. 136 6179-6182 2014 Saccharomyces cerevisiae 24739148
Display the reaction diagram Show all sequences 2.1.1.314729901 Dph7 catalyzes a previously unknown demethylation step in diphthamide biosynthesis J. Am. Chem. Soc. 136 6179-6182 2014 Saccharomyces cerevisiae ATCC 204508 24739148
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