Activity profiling of human deSUMOylating enzymes (SENPs) with synthetic substrates suggests an unexpected specificity of two newly characterized members of the family
c-Myc is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1, SENP7 and RNF4
Characterization of SENP7, a SUMO-2/3-specific isopeptidase
Differential expression of SUMO-specific protease 7 variants regulates epithelial-mesenchymal transition
Proc. Natl. Acad. Sci. USA
Structural insights into the SENP6 loop1 structure in complex with SUMO2
Structure of the human SENP7 catalytic domain and poly-SUMO deconjugation activities for SENP6 and SENP7
J. Biol. Chem.
The deSUMOylase SENP7 promotes chromatin relaxation for homologous recombination DNA repair
The SENP7 SUMO-protease presents a module of two HP1 interaction motifs that locks HP1 protein at pericentric heterochromatin
The SUMO protease SENP7 is a critical component to ensure HP1 enrichment at pericentric heterochromatin
Nat. Struct. Mol. Biol.