EC Number |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism |
PubMed ID |
---|
3.4.21.46 | 753602 |
Complement factor D homolog involved in the alternative complement pathway of rock bream (Oplegnathus fasciatus) Molecular and functional characterization and immune responsive mRNA expression analysis |
Fish Shellfish Immunol. |
55 |
423-433 |
2016 |
Oplegnathus fasciatus |
27311435 |
3.4.21.46 | 752442 |
Complement factor D protects mice from ethanol-induced inflammation and liver injury |
Am. J. Physiol. Gastrointest. Liver Physiol. |
315 |
G66-G79 |
2018 |
Mus musculus |
29597356 |
3.4.21.46 | 754401 |
Design, synthesis, and preclinical characterization of selective factor D inhibitors targeting the alternative complement pathway |
J. Med. Chem. |
62 |
4656-4668 |
2019 |
Homo sapiens |
30995036 |
3.4.21.46 | 752372 |
Discovery and design of first benzylamine-based ligands binding to an unlocked conformation of the complement factor D |
ACS Med. Chem. Lett. |
9 |
490-495 |
2018 |
Homo sapiens |
29795765 |
3.4.21.46 | 754391 |
Discovery of highly potent and selective small-molecule reversible factor D inhibitors demonstrating alternative complement pathway inhibition in vivo |
J. Med. Chem. |
60 |
5717-5735 |
2017 |
Homo sapiens |
28621538 |
3.4.21.46 | 754127 |
Dynamic regulation of platelet-derived growth factor D (PDGF-D) activity and extracellular spatial distribution by matriptase-mediated proteolysis |
J. Biol. Chem. |
290 |
9162-9170 |
2015 |
Homo sapiens |
25678707 |
3.4.21.46 | 753616 |
Molecular characterization, expression and antimicrobial activity of complement factor D in Megalobrama amblycephala |
Fish Shellfish Immunol. |
89 |
43-51 |
2019 |
Megalobrama amblycephala |
30890434 |
3.4.21.46 | 752876 |
Senescent dermal fibroblasts negatively influence fibroblast extracellular matrix-related gene expression partly via secretion of complement factor D |
Biofactors |
45 |
556-562 |
2019 |
Homo sapiens |
31026383 |
3.4.21.46 | 755129 |
Small molecule-induced complement factor D (adipsin) promotes lipid accumulation and adipocyte differentiation |
PLoS ONE |
11 |
e0162228 |
2016 |
Mus musculus |
27611793 |
3.4.21.46 | 732521 |
Alternative complement pathway component Factor D contributes to efficient clearance of tissue debris following acute CCl4-induced injury |
Mol. Immunol. |
64 |
9-17 |
2015 |
Mus musculus |
25467802 |