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Results 1 - 10 of 82 > >>
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EC Number BRENDA No. Title Journal Volume Pages Year Organism PubMed ID
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286752023 Histone deacetylation by Sir2 generates a transcriptionally repressed nucleoprotein complex Proc. Natl. Acad. Sci. USA 100 1609-1614 2003 Drosophila melanogaster 12571358
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286750253 Crystal structure of a SIR2 homolog-NAD complex Cell 105 269-279 2001 Archaeoglobus fulgidus 11336676
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286750369 SIR2 the biochemical mechanism of NAD+-dependent protein deacetylation and ADP-ribosyl enzyme intermediates Curr. Med. Chem. 11 807-826 2004 Saccharomyces cerevisiae 15078167
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286752056 SIR proteins create compact heterochromatin fibers Proc. Natl. Acad. Sci. USA 115 12447-12452 2018 Saccharomyces cerevisiae 30455303
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286751547 Structural basis for the mechanism and regulation of Sir2 enzymes Mol. Cell 13 639-648 2004 Archaeoglobus fulgidus 15023335
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286750904 Highly dissociative and concerted mechanism for the nicotinamide cleavage reaction in Sir2Tm enzyme suggested by ab initio QM/MM molecular dynamics simulations J. Am. Chem. Soc. 130 16721-16728 2008 Thermotoga maritima 19049465
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286750904 Highly dissociative and concerted mechanism for the nicotinamide cleavage reaction in Sir2Tm enzyme suggested by ab initio QM/MM molecular dynamics simulations J. Am. Chem. Soc. 130 16721-16728 2008 Thermotoga maritima ATCC 43589 19049465
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286750905 Transition state of ADP-ribosylation of acetyllysine catalyzed by Archaeoglobus fulgidus Sir2 determined by kinetic isotope effects and computational approaches J. Am. Chem. Soc. 132 12286-12298 2010 Archaeoglobus fulgidus 20718419
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286750907 Azalysine analogues as probes for protein lysine deacetylation and demethylation J. Am. Chem. Soc. 134 5138-5148 2012 Thermotoga maritima 22352831
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286751549 Structural basis for nicotinamide inhibition and base exchange in Sir2 enzymes Mol. Cell 25 463-472 2007 Saccharomyces cerevisiae 17289592
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