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Results 1 - 10 of 82 > >>
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EC Number BRENDA No. Title Journal Volume Pages Year Organism PubMed ID
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286718508 Cloning, purification, crystallization and preliminary crystallographic analysis of the human histone deacetylase sirtuin 1 Acta Crystallogr. Sect. F 67 461-463 2011 Homo sapiens 21505241
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286728857 Inhibitors of the NAD(+)-dependent protein desuccinylase and demalonylase Sirt5 ACS Med. Chem. Lett. 3 1050-1053 2012 Homo sapiens 24900427
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286729164 Histone deacetylase SIRT1 modulates and deacetylates DNA base excision repair enzyme thymine DNA glycosylase Biochem. J. 456 89-98 2013 Homo sapiens 23952905
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286729498 Down-regulation of sirtuin 3 is associated with poor prognosis in hepatocellular carcinoma after resection BMC Cancer 14 297 2014 Homo sapiens 24774224
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286729560 hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase Cell 107 149-159 2001 Homo sapiens 11672523
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286729561 SIRT1 regulates circadian clock gene expression through PER2 deacetylation Cell 134 317-328 2008 Homo sapiens 18662546
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286729603 The discovery of a highly selective 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one SIRT2 inhibitor that is neuroprotective in an in vitro Parkinson's disease model ChemMedChem 10 69-82 2015 Homo sapiens 25395356
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286729638 Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence EMBO J. 21 2383-2396 2002 Homo sapiens 12006491
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286729674 Development and characterization of 3-(benzylsulfonamido)benzamides as potent and selective SIRT2 inhibitors Eur. J. Med. Chem. 76 414-426 2014 Homo sapiens 24602787
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.286729680 Quantitative insights for the design of substrate-based SIRT1 inhibitors Eur. J. Pharm. Sci. 59 12-19 2014 Homo sapiens 24747578
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