EC Number   |
BRENDA No. |
Title  |
Journal |
Volume |
Pages |
Year |
Organism |
PubMed ID |
|---|
   1.14.99.20 | 744612 |
Influence of proton pump inhibitors and VKORC1 mutations on CYP2C9-mediated dose requirements of vitamin K antagonist therapy a pilot study |
Br. J. Haematol. |
167 |
547-553 |
2014 |
Homo sapiens |
25142093 |
| 1.14.99.20 | 672089 |
Bronsted analysis reveals Lys218 as the carboxylase active site base that deprotonates vitamin K hydroquinone to initiate vitamin K-dependent protein carboxylation |
Biochemistry |
45 |
13239-13248 |
2006 |
Leptospira interrogans |
17073445 |
| 1.14.99.20 | 438300 |
Changes in phylloquinone epoxidase activity related to prothrombin synthesis and microsomal clotting activity in the rat |
Biochem. J. |
140 |
435-441 |
1974 |
Rattus norvegicus |
4155625 |
| 1.14.99.20 | 438311 |
Developmental changes of vitamin K epoxidase and reductase activities involved in the vitamin K cycle in human liver |
Early Hum. Dev. |
57 |
15-23 |
2000 |
Homo sapiens |
10690708 |
| 1.14.99.20 | 438308 |
Mutagenesis of vitamin K-dependent carboxylase demonstrates a carboxyl terminus-mediated interaction with vitamin K hydroquinone |
J. Biol. Chem. |
270 |
5305-5311 |
1995 |
Bos taurus |
7890642 |
| 1.14.99.20 | 438306 |
Oxygen dependence of vitamin K-dependent carboxylase and vitamin K epoxidase |
FEBS Lett. |
200 |
71-75 |
1986 |
Rattus norvegicus |
3699166 |
| 1.14.99.20 | 438309 |
Profactor IX propeptide and glutamate substrate binding sites on the vitamin K-dependent carboxylase identified by site-directed mutagenesis |
J. Biol. Chem. |
271 |
17837-17844 |
1996 |
Bos taurus |
8663364 |
| 1.14.99.20 | 438310 |
Propeptide and glutamate-containing substrates bound to the vitamin K-dependent carboxylase convert its vitamin K epoxidase function from an inactive to an active state |
Proc. Natl. Acad. Sci. USA |
94 |
9069-9074 |
1997 |
Bos taurus |
9256436 |
| 1.14.99.20 | 438302 |
The inhibition of vitamin K-dependent carboxylase by cyanide |
FEBS Lett. |
137 |
253-256 |
1982 |
Bos taurus |
6277693 |
| 1.14.99.20 | 674485 |
The vitamin K-dependent carboxylase has been acquired by Leptospira pathogens and shows altered activity that suggests a role other than protein carboxylation |
J. Biol. Chem. |
280 |
34870-34877 |
2005 |
Leptospira interrogans |
16061481 |
