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EC Number Reaction Commentary Reference
Show all pathways known for 6.3.1.21Display the word mapDisplay the reaction diagram Show all sequences 6.3.1.21ATP + formate + N1-(5-phospho-beta-D-ribosyl)glycinamide = ADP + phosphate + N2-formyl-N1-(5-phospho-beta-D-ribosyl)glycinamide - -
Show all pathways known for 6.3.1.21Display the word mapDisplay the reaction diagram Show all sequences 6.3.1.21ATP + formate + N1-(5-phospho-beta-D-ribosyl)glycinamide = ADP + phosphate + N2-formyl-N1-(5-phospho-beta-D-ribosyl)glycinamide possible catalytic mechanism for PurT transformylase. In this mechanism, the breakage of the beta-gamma phosphate bond results in a shift of the Mg2+-formyl phosphate thereby bringing the carbonyl carbon of the formyl phosphate near the amine of glycinamide ribonucleotide (GAR). Asp268 functions to deprotonate the amine of GAR, which then reacts with the carbonyl group of formyl phosphate to release phosphate and formyl-GAR 760559
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