EC Number   |
Reaction |
Reference |
|---|
    5.1.2.1 | (S)-Lactate = (R)-lactate |
direct internal hydride transfer mechanism, symmetrical alpha-carbon intermediate |
2172 |
| 5.1.2.1 | (S)-Lactate = (R)-lactate |
the enzyme does not follow a proton-coupled electron transfer mechanism, but a proton-coupled hydride transfer (PCHT) mechanism. The nickel-pincer cofactor facilitates a proton-coupled hydride transfer (PCHT) mechanism during LarA-catalyzed lactate racemization |
-, 747142 |
| 5.1.2.1 | (S)-Lactate = (R)-lactate |
the Ni-tethered pincer cofactor in enzyme LarA increases reaction barriers and destabilizes NADH-like pyruvate intermediates, due to the less electrophilic Ni cofactor and to the ring strain in the pyruvate intermediates, reaction mechanism, active and transition state structure, modeling |
-, 747571 |
| 5.1.2.1 | (S)-Lactate = (R)-lactate |
transient carbonyl intermediate, carbonyl is in the alpha-position of the enzyme-bound lactic acid |
2171 |
