EC Number   |
Reaction |
Reference |
|---|
    5.1.1.11 | ATP + L-phenylalanine + H2O = AMP + diphosphate + D-phenylalanine |
phenylalanine racemase catalyzes the exchange between a proton in the medium and alpha-hydrogen of Phe. Probably a sulfhydryl group, on the enzyme functions as proton donor and acceptor during the reaction |
2071 |
| 5.1.1.11 | ATP + L-phenylalanine + H2O = AMP + diphosphate + D-phenylalanine |
racemizes Phe in the thioester-bound stage |
2072 |
| 5.1.1.11 | ATP + L-phenylalanine + H2O = AMP + diphosphate + D-phenylalanine |
the amino group of Phe is essential for its binding to the aminoacyl adenylate reaction center. The carbonyl group is not at all or only weakly bound. The benzene ring of Phe which determines substrate recognition also seems to be of minor importance for substrate binding |
2056 |
| 5.1.1.11 | ATP + L-phenylalanine + H2O = AMP + diphosphate + D-phenylalanine |
the enzyme activates both L-Phe and D-Phe to form L-phenylalanyl adenylate and D-phenylalanyl adenylate bound to the enzyme, respectively, and then transfers the L-Phe and D-Phe moiety to the thiol group of the enzyme followed by conversion of its configuration, the D-isomer being the more favorable configuration |
2070 |
