EC Number |
Reaction |
Reference |
---|
4.6.1.19 | an [RNA fragment]-3'-nucleoside-2',3'-cyclophosphate + H2O = an [RNA fragment]-3'-nucleoside-3'-phosphate |
(1b) |
- |
4.6.1.19 | RNA + H2O = an [RNA fragment]-3'-nucleoside-3'-phosphate + a 5'-hydroxy-ribonucleotide-3'-[RNA fragment] |
active site structure, Glu32 is an essential part of the B2-substrate recognition and binding site |
655052 |
4.6.1.19 | RNA + H2O = an [RNA fragment]-3'-nucleoside-3'-phosphate + a 5'-hydroxy-ribonucleotide-3'-[RNA fragment] |
catalytic hydrolysis mechanism, active site structure, the conserved active site residues His39, His92, and His 97 are essential for activity, Glu93 and Lys96 are important |
656479 |
4.6.1.19 | RNA + H2O = an [RNA fragment]-3'-nucleoside-3'-phosphate + a 5'-hydroxy-ribonucleotide-3'-[RNA fragment] |
mechanism |
134487 |
4.6.1.19 | RNA + H2O = an [RNA fragment]-3'-nucleoside-3'-phosphate + a 5'-hydroxy-ribonucleotide-3'-[RNA fragment] |
mechanism of RNA recognition, binding and cleavage by RNase L, overview |
730967 |
4.6.1.19 | RNA + H2O = an [RNA fragment]-3'-nucleoside-3'-phosphate + a 5'-hydroxy-ribonucleotide-3'-[RNA fragment] |
overall reaction |
- |
4.6.1.19 | RNA + H2O = an [RNA fragment]-3'-nucleoside-3'-phosphate + a 5'-hydroxy-ribonucleotide-3'-[RNA fragment] |
Phe101 is important for catalytic activity |
654990 |
4.6.1.19 | RNA + H2O = an [RNA fragment]-3'-nucleoside-3'-phosphate + a 5'-hydroxy-ribonucleotide-3'-[RNA fragment] |
reaction mechanism |
656707 |
4.6.1.19 | RNA + H2O = an [RNA fragment]-3'-nucleoside-3'-phosphate + a 5'-hydroxy-ribonucleotide-3'-[RNA fragment] |
reaction mechanism, His109, Lys108, His104, and His46 are involved |
656707 |
4.6.1.19 | RNA + H2O = an [RNA fragment]-3'-nucleoside-3'-phosphate + a 5'-hydroxy-ribonucleotide-3'-[RNA fragment] |
residues His34, His 83, Glu84, Lys87, and His88 may be involved in catalysis |
654994 |