EC Number   |
Reaction |
Reference |
|---|
    4.2.3.1 | O-phospho-L-homoserine + H2O = L-threonine + phosphate |
analyzed crystal structure gives new insights into the catalytic mechanism of threonine synthase in general, specifically by suggesting the direct involvement of the phosphate moiety of the cofactor, rather than the inorganic phosphate product, in transferring a proton from C4 to Cgamma in the formation of the alphabeta-unsaturated aldimine |
-, 728848 |
| 4.2.3.1 | O-phospho-L-homoserine + H2O = L-threonine + phosphate |
inhibitor studies concerning mechanism, model of stepwise catalytic mechanism |
137559 |
| 4.2.3.1 | O-phospho-L-homoserine + H2O = L-threonine + phosphate |
mechanism |
137550, 137552, 137560, 137561 |
| 4.2.3.1 | O-phospho-L-homoserine + H2O = L-threonine + phosphate |
mechanism of phosphohomoserine dephosphorylation/deamination activity |
137546 |
| 4.2.3.1 | O-phospho-L-homoserine + H2O = L-threonine + phosphate |
reaction proceeds via phospate removal and isomerization from primary to secondary alcohol |
137544 |
| 4.2.3.1 | O-phospho-L-homoserine + H2O = L-threonine + phosphate |
reaction proceeds via phosphate removal and isomerization from primary to secondary alcohol |
663091, 665733, 666989 |
| 4.2.3.1 | O-phospho-L-homoserine + H2O = L-threonine + phosphate |
the phosphate ion released from O-phospho-L-homoserine by gamma-elimination acts as the base catalyst for the addition of water at Cbeta of the alpha-aminocrotonate aldimine, thereby providing the basis of the reaction specificity. The phosphate ion also accelerates the protonation/deprotonation at Cgamma |
-, 715628 |
