EC Number   |
Reaction |
Reference |
|---|
    3.5.3.12 | agmatine + H2O = N-carbamoylputrescine + NH3 |
- |
- |
| 3.5.3.12 | agmatine + H2O = N-carbamoylputrescine + NH3 |
like other GME hydrolases the enzyme possesses a high pKa active site Cys, suggesting that the enzyme employs a reverse protonation mechanism |
718884 |
| 3.5.3.12 | agmatine + H2O = N-carbamoylputrescine + NH3 |
the enzyme does not show activity of EC 2.1.3.3, ornithine carbamoyltransferase, EC 2.1.3.6, putrescine carbamoyltransferase, and EC 2.7.2.2, carbamate kinase, while putrescine synthase is a multifunctional enzyme, overview |
657259 |
| 3.5.3.12 | agmatine + H2O = N-carbamoylputrescine + NH3 |
the plant enzyme also catalyzes the reactions of EC 2.1.3.3, ornithine carbamoyltransferase, EC 2.1.3.6, putrescine carbamoyltransferase, and EC 2.7.2.2, carbamate kinase, thus functioning as a putrescine synthase, converting agmatine and ornithine into putrescine and citrulline, respectively, Cys180 and Cys366 are involved in catalysis but are not essential, residues are located in the substrate binding pocket |
655571 |
